High expression of UBD correlates with epirubicin resistance and indicates poor prognosis in triple-negative breast cancer

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High expression of UBD correlates with epirubicin resistance and indicates poor prognosis in triple-negative breast cancer

BACKGROUND Triple-negative breast cancer (TNBC) is a heterogeneous subtype of breast cancer that is prone to recurrence and metastasis with worse prognosis. Epirubicin-based chemotherapy is of great importance for patients with TNBC, but resistance to epirubicin severely limits the application of this drug and this has emerged as a major problem in the treatment of TNBC. The ubiquitin protein D...

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ژورنال

عنوان ژورنال: OncoTargets and Therapy

سال: 2015

ISSN: 1178-6930

DOI: 10.2147/ott.s81214